Motor Neurone Disease

Lou Gehrig's disease and amyotrophic lateral sclerosis (ALS) are other names for motor neuron disease (MND). Although it can start in many places of the body, it is a neurological disease that advances quickly and frequently starts with weakness in the hands, feet, or voice muscles. It can also progress in different ways and at varying speeds.

Motor neurone disease symptoms (MND)

  • Fatigue
  • Muscle wasting, weight loss
  • Emotional instability
  • Cognitive change
  • Respiratory changes
  • Muscle aches, cramps, and twitching
  • Clumsiness, stumbling
  • Weakness or changes in hands, arms, legs, and voice
  • Slurred speech, swallowing or chewing difficulty
  • Fatigue
  • Muscle wasting, weight loss
  • Emotional liability

MND causes

MND causes
  • Genetic factors
  • Exposure to specific poisons and chemicals, and viral and chemical exposure
  • Nerve growth factors; immune system-induced inflammation and neuronal injury
  • The maturation, growth, and repair of motor neurons
  • MND's effects on caregivers

    The person's physical condition will change quickly as MND worsens, necessitating more help from a caregiver. Both the caregiver and the MND patient will eventually require higher and higher degrees of emotional and physical support.


    Although MND is still incurable, many of its symptoms are manageable. Hence, always seek treatment from the best hospital for neurology.

    Dr. Manish Gupta
    Associate Director
    Department of Neurology
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